This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. Comprecel MCC (Microcrystalline Cellulose) is a pharmaceutical excipient derived from nature's most abundant and renewable raw material-wood pulp. ( If you are already a ChemPoint customer then sign up for access to our online ordering website. MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 4 of 4 15. We are the leading manufacturer of Microcrystalline Cellulose coated with - RC 581 Grade in the industry. Alginates from IFF are an excellent choice for consistent performance in a variety of applications. Created Date: 2/10/2020 8:51:41 PM . >> These co-processed products are designed to solve complex formulation problems, simplify manufacturing processes, and deliver significant cost savings. Watch Now. 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . Researcher's newest research report, the "Wood Pulp Based Microcrystalline Cellulose Industry Forecast" looks at past sales and reviews total world Wood Pulp Based Microcrystalline Cellulose sales in 2022, providing a comprehensive analysis by region and market sector of . Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Page 1 of 9. w !1AQaq"2B #3Rbr Safety Data Sheet for Cellulose microcrystalline 102331. %PDF-1.5 IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. Truly distinctive drug delivery solutions. endobj United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical. Trademarks: Avicel PH-102. Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * It is widely used within the pharmaceutical, food, and cosmetic sectors as a formulation aid. Alginates also function as actives in some anti-reflux products. PDF (4.11 mb) Footer menu 1. Microcrystalline Cellulose; Cellulose; Functions. The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. By utilizing proprietary co-processing technologies, Dupont also manufactures LATTICE NTC products. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Avicel PC 611 Microcrystalline Cellulose CHEMICAL FAMILY: Carbohydrate, Cellulose Derivative SYNONYMS: Microcrystalline cellulose (INCI name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethylcellulose GENERAL USE: Personal Care MANUFACTURER FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 (General Information) msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Ireland) 2. SDS. Avicel Microcrystalline cellulose is available in many grades, which differ in particle size, bulk density, and moisture content. Product Name Cellulose microcrystalline. Assay: 0.98 Appearance: Off white to slight yellow solid Package: 1L 5L 10L 25L bottle Storage: Stored in shaded, cool and dry places Transportation: Handle with cares to avoid damaging the packages. <> Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. Have an order or account question, find answers in our Online Support articles. PharmaCentral 2021 . . POLYOX resins are nonionic polyethylene oxide solubility polymers. X\o^ Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. 6 0 obj PDF (28.38 mb) 2022 Corporate Fact Sheet. Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. Avicel PC 611 (FMC Biopolymer) Supplied by. Cellulose, microcrystalline | C14H26O11 | CID 14055602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . !(!0*21/*.-4;K@48G9-.BYBGNPTUT3? Explore how we work and why we apply science and creativity for a better world to everything we do. Quick Links. The representative usage of Avicel PH-101 and Avicel PH-102 Microcrystalline cellulose in wet granulation and direct compression is shown in the following two examples. (Microcrystalline Cellulose) DATE PREPARED: 1/7/2016 Page 1 of 4 Section 1. This unique functionality can be used in a diversity of applications such as controlled release dosage forms, enteric coatings, microencapsulation and stabilization in solutions and suspensions. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. Assay for carboxymethycellulose sodium, wt % 8.3 to 13.8 . Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. . Product Specifications: Chemical and Physical: Loss on drying, % NMT 6.0* Viscosity, cps, 1.2% solids, 120 sec 39 to 91 . JFIF ` ` ZExif MM * J Q Q Q C This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. The polymers added organosolubility further creates advantages for employing HPMC in solvent spray-drying applications. We respect your privacy FMC Privacy Policy. Microcrystalline Cellulose / Avicel PH-102. These grades have particle sizes ranging from <30 to approximately 200. Avicel Microcrystalline Cellulose: Chemical Identifiers. The typical mean particle size is 20200 m. Avicel PH-101. 2008-2023 ChemPoint. To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . Avicel Microcrystalline cellulose also serves as a moisture adsorbent and as a general-purpose formulation improver. : 160182. All rights reserved. pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q c Dh)#t'kTfIZT1-_y"+wXj,qo!~ozc}ZemZ``$'vj{, Ga;]2iY*DIh~F3Z!.pkL:bHHBTbIcw9.Xo$4,?On4s=R,KLz /M|#PF(j%j oF2[5 ,rx)bd1$LM4Dc-d\@W D?A?L/7>s]-};Z if^+e3}AeQ# U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. A family of polysaccharide products that allow distinctive drug delivery solutions. No. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose . Van Veen, G.K. Bolhuis, Y.S. MATERIAL SAFETY DATA SHEET Avicel PH Microcrystalline Cellulose MSDS Ref. MSDS Ref. Generally, these can be classified into two broad groups: Standard grades, and Co-processed grades. 1.3. ). %PDF-1.4 . iQuLyI4D@yq#u0dZt=0?QUz{K6by_C"vW~Nj$bo? LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such . Heavy metals, % NMT 0.001 FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 . . 0.25 - 0.37. It is an excipient approved for use in pharmaceutical products and is also GRAS listed and accepted for use as a food additive in Europe and the United States and is included in the FDA Inactive Ingredients Database (oral: powders, suspensions, syrups, and tablets; topical & vaginal products). LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. Go to Investor Relations. It is . Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . From anti-reflux to biomedical implants, alginates are uniquely suited for a wide range of applications. Avicel RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel CL-611 is a stabilizer for reconstitutable or dry suspension formulations. \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C PipEAz_xO;`cZsC0qcx;@tp]c*T7ge @Mty?]@SNmpf/]q#I,G1I?SR.@z*Xb KjR hb{T$CQrr Yx%O@~57eL5S\r-|EZ)Y.C]KuIlW]@12KY,S]C"e%b*|YX122igjl; @! ,}b;XQ})+l{~d_=sUtl V"CbKas+;fc>]bt#F,Md]]!5xae ;}rr^NI]rUc^,5Lc(fyyp*a=~U}WveuTLYX/ _V{#* g(*Rrm0gyv9i@0UT:A+{eW/y BS3_!Qv rt^BN! A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. : 9004-34-6 Date Approved: 01/31/2008 . <> FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Combines good flow and high compactibility. Avicel Microcrystalline Cellulose Physical Properties. Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. common form is used in vitamin supplements or tablets. The product would later go on to be commercialized under the brand name Avicel by FMC Corporation. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose using a Waring Blender. Frijlink, Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) Microcrystalline Cellulose, European journal of Pharmaceutics and Biopharmaceutics, 59 (2005) 133-138. The global Microcrystalline Cellulose (Mcc) market size is projected to reach multi million by 2026, in comparison to 2022, at unexpected CAGR during 2022-2026. Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. Aqueous suspensions of microcrystalline cellulose have . Cellulose microcrystalline. It . Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. 102331. : 1. Battista, O. <> P}MFbN#[>r(y The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. The range of products includes three basic types of carrageenan kappa, iota and lambda from various species of red seaweed. Microcrystalline Cellulose (MCC) MSDS 1. Superior Performance: Provides excellent water uptake and rapid swelling . Avicel Microcrystalline Cellulose: A Guide to Grades and Uses, Working Hours (Mon to Friday): 08:30 - 17:30, legendary Canadian-born chemist, Orlando Aloysius Battista, United States Pharmacopoeia and National Formulary, United States Food and Drug Administration, Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g), https://doi.org/10.1016/0378-5173(95)04231-8, https://doi.org/10.1016/j.ejpb.2004.05.009, https://doi.org/10.1002/9783527682935.ch04, Pharmaceutical Acronyms and Abbreviations, Glossary of Terms Used in the Pharmaceutical Industry, Standard Terms & Conditions Of Sale Of Goods And Services, 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose. No. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. Avicel Microcrystalline cellulose is composed of insoluble fibre and does not contribute any other material of nutritional importance. <> G2W4de=u183KGH{ vQ#4:1\wc PDF (2.77 mb) 2021 FMC Sustainability Report. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) INCI. MATERIAL SAFETY DATA SHEET. ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" Comments: The human studies including the use of radiolabelled microcrystalline cellulose show complete absence of digestion or absorption. Home. Microcrystalline cellulose (MCC) is a pure partially depolymerized cellulose synthesized from -cellulose precursor (type I), obtained as a pulp from fibrous plant material, with mineral acids using hydrochloric acid to reduce the degree of polymerization. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. q9;v80 High performance lubricant that brings more to the tablet. Chemical Formula: (C6H10O5)n 1.4. Avicel is one of the best-known pharmaceutical excipient brands and, without doubt, one of the most frequently used raw materials in solid oral product formulation and manufacture. The most. Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. l~5C The chemical structure of cellulose is shown below: In the biosynthesis of cellulose, two molecules of -D-glucose molecules combine via a condensation reaction (elimination of one molecule of water) to form the so-called cellobiose unit. ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& However, with many different grades (standard and specialty) on offer, how do you select the correct material for your needs? HMo@9, U Q!R/1*;` It is available in different grades and particle sizes. /Contents 4 0 R Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. 1.3. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. Powder becomes slippery when wet. % endobj The current product range and recommended usage are summarised below: Microcrystalline Cellulose is currently listed in the United States Pharmacopoeia and National Formulary, the European Pharmacopeia, the Japanese Pharmacopoeia, the British Pharmacopoeia, in addition to the Indian and Chinese Pharmacopeia, to name but a few. "R}~Q:~pgg'"l/O:OV~ @zo7g;)K;=d'}z8}7w7?Iuw?w~ikK^^'d4k;g_u_LOC6($uiz["Dw#j{ogw~0B"ty'{DqXmImPiww#({LDo^/w;?EW>;b$l/fmQ-1GG/jls}>N\UbZWi,`:O?e;hD8}uC?L{yiD>_2?0 :f =eU}|r=r?P5){{o:tzY- F kNdOaM;p0Nmm7A!Va/eWzgT5vw Ur?0J. (&E. MATERIAL SAFETY DATA SHEET Avicel RC/CL Microcrystalline Cellulose and Sodium Carboxymethylcellulose MSDS Ref. pfTr^i5wOg)y .6 68ZWN hZB{u7ps@uWm 2#@+o/Z {vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ The short-term limit for total inhalable dust is 20 mg/m3. MCC helps in the formation of spheres because of its . It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. if interested in purchasing or obtaining a sample for assessment, you should contact Dupont themselves directly. endobj CAS 9004-34-6, pH 5 - 7.5. 0.25 - 0.37. 2 0 obj However, consumption of large quantities of the material may have a laxative effect. ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM /Parent 3 0 R 5 0 obj ( Product Name: Microcrystalline Cellulose E460 1.2. In extrusion-spheronisation, it is the excipient of choice. AFFINISOL hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer that can help optimize solubility enhancement of poorly soluble drugs by maintaining stable solid dispersions and inhibiting API crystallization. METHOCEL cellulose ethers are water-soluble polymers derived from cellulose. Avicel is a brand name by Dupont for grades of Microcrystalline cellulose. This Microcrystalline Cellulose . Currently, it is marketed both directly and indirectly (through distributors) depending on the country in question. (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC ECOLOGICAL INFORMATION ECOTOXICITY Practically nontoxic to fish: Rainbow trout LC50 (96hr) > 100%, saturated solution (Microcrystalline cellulose, Avicel PH-101) PERSISTENCE AND BIODEGRADABILITY Inherently biodegradable. Request media, explore upcoming events and read our latest updates. 3 0 obj SCMm_>x^O9l (n. Looking for FMC'searnings news? The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils. Description: Microcrystalline Cellulose E460 is a term for refined wood pulp manufactured through plant fibre hydrolysis. Avicel Microcrystalline Cellulose is a safe and non-hazardous material that is widely used in pharmaceutical formulations and food products (as a bulking agent and to add crispness). Microcrystalline cellulose is a commonly used excipient in the . Delivering efficient and robust formulations. Avicel Microcrystalline cellulose occurs as a white, odourless, tasteless, fibrous powder composed of porous particles. As some of the data above show, microcrystalline cellulose possesses unique physicochemical properties that set it apart from native cellulose. Microcrystalline Cellulose (MCC) Manufacturing Industry. Doses up to 30 g per day appear to be . This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication MATERIAL SAFETY DATA SHEET Version: 1.0 1. Microcrystalline cellulose was negative in the Ames mutagenicity assay [FMC Study Number I91-1189], and caused no As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. Regulatory Information Product and Company Identification . Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses CN103842425B . 4 0 obj They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, With an account you can check out faster, view your online order history and access your shopping bag or saved items from any device. Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. Some substance identifiers may have been claimed confidential, or may . bEI3%UxI"M_1)5b/c;/\~3:?/9S\\9/%I3nn2foO^MgX0n: O Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. It is generally regarded as a relatively nontoxic and non-irritant material that is safe for human and animal consumption. Apply today! In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. << Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. Kristensen, T. Schfer, P. Kleinebudde, Direct pelletization in a rotary processor controlled by torque measurements. SDS - Safety Data Sheet. SUBSTANCE IDENTIFICATION 1.1. The process is relatively basic; and starts with treating cellulose, obtained as a high-grade pulp obtained from fibrous plant material, with mineral acids, followed by purification and spray-drying. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. 9,LL!z SEM micrographs of microcrystalline cellulose (MCC) models with a scale bar of 100 m [1] . $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ? The cellulose molecule is formed through repeated condensation of cellobiose units. CAS #: 9004-34-6 1.6. << Are you looking for information about products and services by region? 1. Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. cas:9032-51-3 msds CELLULOSE PAB. Microcrystalline cellulose (MCC) for industrial purposes is usually obtained from wood pulp and purified cotton linters. << Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. FMC, JRS and Mingtai were estimated to hold for . To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CLtrade mark as overlay media in the plaque and plaque-inhibition assay of influenza viruses. *r_ *?~4$ &0Y# Find answers in our support articles. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA Cu:3(]N"AQdUt~h|P It is, however, a good source of fibre. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. The 'Substance identity' section is calculated from substance identification information from all ECHA databases. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. No. However, it yields non-digestible fibre. Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 1 of 4 1. Accumulation of overhead settled dust may form explosive concentrations in air when disturbed and dispersed. To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. No. stream 130. Place an order online, track your orders, download SDS and TDS, and see your quotes, all in one secure place. Avicel RC-591 & CL-611 - Description. Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. ( >z+{!A6wy @nLK3R#hRn sba3;b61V:#Z3X,*?RC!wPmqd7WkA'aZMt6PFV3SEvlY'=p.mn[I{puc\6'ZIyI%rD'zA!"t3I2F ^R;LK,?:&THv*y^K> o0Af?J9J-{s2&cCn)32ADzl%sS5O~J[ Microcrystalline Cellulose Side Effects. Catalog Number 102331. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. Microcrystalline cellulose (C6H10O5)n is refined wood pulp. Synergies to simplify formulation challenges and reduce operational costs. <> All Rights Reserved. The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. endobj stream 2021 Annual Report. More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. %PDF-1.3 YUMPU automatically turns print PDFs into web optimized ePapers that Google loves. Manufacturer: FMC BioPolymer. The figure below illustrates the structural organisation of cellulose within plants. Dyvo5bp#bR W7~IF C" d6zLz~!#>@HO}sx;hm>> Revision No. <> Dupont acquired the microcrystalline cellulose business of FMC Corporation in 2017. Learn about FMC's differentiated biologically-based crop solutions.